Georgetown University
 

Final Exam

Course Home Page
 

Instruction for Submission:  

  1. Submit your answers in one Microsoft Word document
  2. Submit you answers in Blackboard.

Question 1: Using the attached sensitivity and specificity estimates for Charlson and MM Index, create two receiver operating curve on the same chart.  Label the X-axis and Y-axis.  Provide a legend inside the plot area.  Calculate area under the curve for each curve.  Which index is more accurate?

Charlson MM Index
Sensitivity Specificity Sensitivity Specificity 
0 1 0 1
0.017 1.000 0.001 1.000
0.038 1.000 0.061 0.994
0.099 1.000 0.204 0.975
0.232 0.997 0.487 0.920
0.435 0.971 0.867 0.739
0.748 0.801 0.938 0.620
0.818 0.653 0.988 0.366
0.818 0.653 0.998 0.110
0.818 0.653 1.000 0.006
0.818 0.653 1.000 0.001
0.818 0.653 1 0
1 0 1 0
 

Question 2: Score the Multi-Morbidity index using ontological adjustments for rare diagnosis with less than 30 cases. Report the likelihood ratios associated with top 20 diagnoses

Question 3:  In the body system model developed in the course, break cardiovascular illness into the following additional 9 systems:

Using the above body systems and the original list of non-cardiovascular body systems, to predict prognosis of the patient for mortality in 6 months.  Report the area under the receiver operating curve for the new body system predictions. 

 

 
Copyright 2021 Farrokh Alemi, Ph.D. Most recent revision 04/29/2021.  This page is part of the course on Electronic Health Record Configuration and Data Analysis.