For this assignment you can use any statistical software you are familiar with or use R. By end of the semester you are to (a) request data, (b) re-analyze existing data using procedures learned in
this course, and (c) draft the paper to be submitted to a peer reviewed journal.
The work on this assignment is done individually but students are
encouraged to help each other and interact with each other. In
writing the paper, follow the protocol for reporting of observational
- At first class, identify your source of data and complete the application for it. You could rely on:
- Any observational data from a medical record that you have
- Data from NIMH funded research projects. These are often
from randomized clinical studies. The available data
include projects on effective treatments for mental illness
including depression, autism, and schizophrenia.
Treatments include antidepressants, cognitive behavioral
counseling, and psychotic medications
- Any other available data that is pre-approved by the
- By 4th week of class complete a one page literature review on
the topic you have chosen with comprehensive references to all
published material. The literature review is short (not to
exceed one page) but the list of references is long. You need
to at least refer to the main article that came out of the data and
their major findings as well as any articles that cite it.
Describe the controversy and the evidence for it. Be brief.
- By 6th week of class. Summarize the data. Prepare Table 1
describing the data.
- By 8th week, prepare the method section. Select a treatment and
evaluate the effectiveness of treatment in different
sub-populations, controlling for covariates.
- By 10th week, circulate your paper to the instructor and one
other student for constructive comments
- By 13th week, draft the final version of the paper in the format
required for submission to peer review journal.
This page is part of the course on
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