Lecture: Semester Long Project  



For this assignment you can use any statistical software you are familiar with or use R.  By end of the semester you are to (a) request data, (b) re-analyze existing data using procedures learned in this course, and (c) draft the paper to be submitted to a peer reviewed journal.   The work on this assignment is done individually but students are encouraged to help each other and interact with each other.  In writing the paper, follow the protocol for reporting of observational studies.  Read►

  1. At first class, identify your source of data and complete the application for it. You could rely on:
    • Any observational data from a medical record that you have access to.
    • Data from NIMH funded research projects. These are often from randomized clinical studies.  The available data include projects on effective treatments for mental illness including depression, autism, and schizophrenia.  Treatments include antidepressants, cognitive behavioral counseling, and psychotic medications  Data►
    • Any other available data that is pre-approved by the instructor
  2. By 4th week of class complete a one page literature review on the topic you have chosen with comprehensive references to all published material.  The literature review is short (not to exceed one page) but the list of references is long.  You need to at least refer to the main article that came out of the data and their major findings as well as any articles that cite it.  Describe the controversy and the evidence for it.  Be brief. 
  3. By 6th week of class.  Summarize the data. Prepare Table 1 describing the data.  
  4. By 8th week, prepare the method section. Select a treatment and evaluate the effectiveness of treatment in different sub-populations, controlling for covariates.  
  5. By 10th week, circulate your paper to the instructor and one other student for constructive comments
  6. By 13th week, draft the final version of the paper in the format required for submission to peer review journal.

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